Today, without thinking about this that how rejuvenation techniques are varied and effective, we cannot deny this fact that aging is inevitable, and its process continues uninterrupted. Our face not excluded from this process, and one of the most common methods that today used to solve this defect is filler injections. With increasing life expectancy and aging of the society has increased the target or goal populations (usually aged between 35 to 60 years) which require the use of these techniques. Fillers divided into two categories: permanent and Non- permanent. (Permanent fillers include biopolymer material and silicon that is out of this paper), Non-permanent fillers today that created more applicants and fans are divided into different types, such as:
- Bovine Collagen
- Human Collagen
- Gels containing Hyaluronans (Hyaluronic Acid)
- Calcium Hydroxyapatite: such as Radiesse Gel
- Sculptra: such as poly- lactic-acid fillers
The characteristics of non-permanent filler are that gradually degraded and destroyed and will need to repeat again, it allow person to change her desire depend on her taste overtime. It may also make little side effects which are divided into three categories:
- Product related complication allergic reaction, granuloma and vascular occlusion
- Injection related sequela: needle marks bruising, redness, and Edema
- Technique-related sequela: Acne type eruption, transient, lumpiness palpable material, visible material through the skin, Asymmetry, under or over correction
The Filler that is injected in the most of clinics in our country is the form of hyaluronic acid. This …. for the first time in 1934, were extracted from the bovine vitreous of cow’s eye, in fact, consists of two glucose that bind together, and It is interesting to note that in whites of egg also it can be found.
In 1970, the first medical form of this product was marketed with the brand name Bio matrix. Then, the second generation of this product, which is called cross-Linking, has been dedicated to market. During this process, stability and biocompatibility of the materials increased and actually the factor that formes the durability and stability of the gel filler today is the number of cross linking.
Hyaluronic acid used in the all intercellular spaces. It enhances and existes the role of flexibility in the intercellular space, at the aging process connective tissue cells lose their ability to produce hyaluronic acid.
in addition, the molecular weight of hyaluronic acid is decreased therefore it cannot keep a water molecule like before, those end to reduce the size, skin laxity and tissue flexibility. Therefore the injection of this connective tissue to maintain the shape, size, texture and moisture of connective tissues and correct of the aging process, as the body has own system for absorbing hyaluronic acid, it is natural that the durability of these fillers are temporary and gradually disappear.
The new generation of hyaluronic acid fillers obtain by the techniques of DNA Recombinant bacteria (Streptococcus), Gram-positive. Generally any person between the ages of 30 and 60 years old can benefit from the injection of hyaluronic acid, but this applies for women who are worried of aging on their faces are more suitable.
In men, this filler is more effective in the nasolabial folds (smile lines) and (frown lines).
In young women, most of the times at lips but It can be useful in other area like, nasolabial folds, glabellar, cheeks, chin, under eyes, temple folds, forehead and neck.
All these injections have been done at Mehr Clinic under sterile conditions and with local anesthetic.
- Quick and acceptable results after injection
- Negligible effects after injection
- User friendly
- Non-migrate (unlike the previous generation of fillers)
- These fillers are non-toxic and does not cause cancer
- Well compatibility with body and tissues
- Acceptable duration